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Poster

Session: Session 1 Presenting Authors at Posters (Odds)

P-371 - Investigating the Role of Arabidopsis RIN4-like/NOI Proteins in Plant Innate Immunity

Monday, July 14, 2025
13:30 - 15:15  
Location: Confex Hall 3
Subcellular dynamics and signaling in host-microbe interactions

    Presenting Author(s)

  • DK

    Dohee Ko

    Korea University
    Seoul, Seoul-t'ukpyolsi, Republic of Korea

    • Author(s)

  • HL

    Huiwon Lee

    Korea University
    Seoul, Seoul-t'ukpyolsi, Republic of Korea

  • HK

    Harin Kim

    University of Tübingen
    Tübingen, Baden-Wurttemberg, Germany

  • JK

    Jumi Kim

    Korea University
    Seoul, Seoul-t'ukpyolsi, Republic of Korea

  • EC

    Eui-Hwan Chung

    Korea University
    Seoul, Seoul-t'ukpyolsi, Republic of Korea

RPM1-interacting protein 4 (RIN4) plays a crucial role in two-tiered plant innate immunity, mediating both pattern-triggered immunity (PTI) and effector-triggered immunity (ETI). Pseudomonas syringae type III effectors, secreted via the type III secretion system (T3SS), target and modify RIN4, thereby inducing effector-triggered susceptibility (ETS). The modification of RIN4 triggers ETI, recognized by plant nucleotide-binding and leucine-rich repeat (NLR) immune receptors. RIN4 harbors two functionally conserved nitrate-induced (NOI) domains, and the Arabidopsis Col-0 genome encodes 14 additional genes containing NOI domains, considered as RIN4 paralogs. Among these 14 paralogs, several interact with three structurally distinct type III effectors—AvrB, AvrRpm1, and AvrRpt2—suggesting that bacterial effectors target additional NOI-containing proteins to subvert PTI and enhance virulence. Collectively, these findings reveal that NOI domain-containing proteins share similarities with RIN4 but play distinct roles.