Skip to main content
ISMPMI Congress 2025 Main banner
Icon Legend
This session is not in your schedule.
This session is in your schedule. Click again to remove it.

Poster

Session: Session 2 Presenting Authors at Posters (Odds)

P-393 - A feedback loop between microbiota and jasmonate signaling pathway modulates plant growth and stress responses

Wednesday, July 16, 2025
13:30 - 15:15  
Location: Confex Hall 3
Plant Regulation of biotic and abiotic stress – trade-offs

    Author(s)

  • TL

    Tung-Tse Lu

    Institute of Plant Microbial Biology (IPMB), Academia Sinica
    Taipei, Taipei, Taiwan (Republic of China)

  • MI

    Miguelito Isip

    Institute of Plant Microbial Biology (IPMB), Academia Sinica
    Taipei, Taipei, Taiwan (Republic of China)

  • CH

    Chiao-Jung Han

    Post-doc
    Institute of Plant Microbial Biology (IPMB), Academia Sinica
    Taipei, Taipei, Taiwan (Republic of China)

  • HS

    Hung-Jui Sophia Shih

    Institute of Plant Microbial Biology (IPMB), Academia Sinica
    Taipei, Taipei, Taiwan (Republic of China)

  • SS

    Syukur Syukur

    Institute of Plant Microbial Biology (IPMB), Academia Sinica
    Taipei, Taipei, Taiwan (Republic of China)

  • SP

    Silvina Perin

    Max Planck Institute for Plant Breeding Research
    Cologne, Nordrhein-Westfalen, Germany

  • PL

    Po-An Lin

    National Taiwan University
    Taipei, Taipei, Taiwan (Republic of China)

    • Presenting Author(s)

  • KM

    Ka-Wai Ma

    Assistant Research Fellow
    Institute of Plant and Microbial Biology (IPMB), Academia Sinica
    Taipei, Taipei, Taiwan (Republic of China)

The model plant Arabidopsis thaliana harbors taxonomically structured microbial communities, collectively known as the microbiota. Plant microbiota can enhance host fitness. However, microbial imbalances can occasionally arise, leading to deleterious effects—a phenomenon known as dysbiosis. Through a genetic screen using defined synthetic bacterial communities, we identified an Arabidopsis Class III peroxidase mutant, per5. per5 exhibits an altered microbial profile, an overall increase in microbial load, and microbiota-dependent growth defects. However, microbiota reconstitution experiments using CRISPR-edited PER5 null mutants suggested that yet unidentified genetic determinant(s) contribute to dysbiosis. Transcriptomic and metabolomic analyses revealed that the jasmonic acid (JA) pathway is upregulated in per5 in response to microbiota. Treatment of plants with JA pathway inducers partially reproduced dysbiosis phenotypes in wild-type plants, suggesting a feedback loop involving microbiota and plant jasmonate pathway. Upregulation of JA is known to affect plant stress adaptation. However, its hyperactivation as in per5 plants results in altered sensitivity to various stressors, including bacterial pathogens, herbivory insect and salt. Our findings provide evidence that regulation of the bacterial microbiota, in conjunction with JA signaling, is essential for maintaining homeostatic plant-microbiota interactions, and proper growth and responses to environmental stresses.