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Poster

Session: Session 1 Presenting Authors at Posters (Evens)

P-144 - Avr-R interactions contribute to non-host resistance of wheat against non-adapted Zymoseptoria species

Tuesday, July 15, 2025
09:55 - 11:30  
Location: Confex Hall 3
Microbial infection strategies (pathogens & non-pathogens)

    Author(s)

  • LM

    Lukas Meile

    Polytechnic University of Madrid
    Madrid, Madrid, Spain

  • CP

    Coraline R Praz

    Polytechnic University of Madrid
    Madrid, Madrid, Spain

  • IV

    Inés Vegas-Lorenzo

    Centro de Biotecnología y Genómica de Plantas (CBGP), Universidad Politécnica de Madrid (UPM)- Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA/CSIC), Madrid, Spain
    Madrid, Madrid, Spain

  • CL

    Cecile Lorrain, Dr (she/her/hers)

    Junior Group Leader
    ETH Zurich
    Zurich, Zurich, Switzerland

  • CS

    Cyrille SAINTENAC

    Doctor
    INRAE GDEC
    CLERMONT FERRAND(CLERMONT-FERRAND), Auvergne, France

    • Presenting Author(s)

  • AS

    Andrea Sánchez-Vallet

    Centro de Biotecnología y Genómica de Plantas (CBGP), Universidad Politécnica de Madrid (UPM)- Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA/CSIC), Madrid, Spain
    Madrid, Madrid, Spain

Resistance of an entire plant species against all strains of a pathogen species is known as non-host resistance (NHR) and is considered more durable than race-specific resistance. These two types of resistance are generally thought to be governed by distinct mechanisms. However, recent work in our lab and others suggested that Avr-R interactions, a hallmark mechanism of race-specific resistance, might also contribute to NHR. We use the closest relatives of wheat pathogen Zymoseptoria tritici, which are not adapted to wheat, to study the contribution of Avr-R interactions to wheat NHR. When expressed in Z. tritici, homologs of Avr3D1, AvrStb9, and AvrStb20q from non-adapted species of Zymoseptoria induce resistance in wheat in a cultivar-specific manner, indicating a gene-for-gene interaction. Like Z. tritici, the non-adapted pathogen Z. ardabiliae can recognize wheat stomata as penetration sites and activate its infection machinery, including the induction of the expression of the Avr3D1 homolog. Deletion of this Avr3D1 homolog in Z. ardabiliae led to an enhanced formation of asexual fruiting bodies on wheat. These results indicate that Avr-R interactions can govern NHR and that loss of Avr genes might contribute to the emergence of new diseases.