Skip to main content
ISMPMI Congress 2025 Main banner
Icon Legend
This session is not in your schedule.
This session is in your schedule. Click again to remove it.

Poster

Session: Session 1 Presenting Authors at Posters (Odds)

P-071 - Recognition of microbial glycoside hydrolase 12 proteins by receptor-like protein RXEG1 confers broad spectrum disease resistance

Monday, July 14, 2025
13:30 - 15:15  
Location: Confex Hall 3
Extracellular & Intracellular non-self recognition & signaling

    Presenting Author(s)

  • YW

    Yan Wang

    Nanjing Agricultural University
    Nanjing, Jiangsu, China (People's Republic)

    • Author(s)

  • mZ

    mengzhu Zeng

    Nanjing Agricultural University
    Nanjing, Jiangsu, China (People's Republic)

  • YW

    Yuanchao Wang

    Nanjing Agricultural University
    Nanjing, Jiangsu, China (People's Republic)

Plant diseases significantly reduce crop yields, posing a serious threat to global food security. Boosting genetic resistance in plants is a key strategy to mitigate the impact of plant diseases on agricultural productivity. The leucine-rich repeat receptor-like protein RXEG1 recognizes the glycoside hydrolase 12 (GH12) protein XEG1 secreted by Phytophthora sojae and triggers plant immune responses. In this study, we demonstrate that RXEG1 broadly recognizes and inhibits the hydrolase activity of multiple GH12 proteins from oomycete and fungal pathogens. Expression of RXEG1 in soybean and cotton enhances resistance to a range of pathogens without negatively affecting plant growth. Our findings highlight that RXEG1’s recognition of GH12 proteins enables broad-spectrum resistance against economically significant pathogens.